HM1-M52H6
Mouse HMGB1 Protein, His Tag (MALS verified)
Cannot supply to this region.
- SKU:
- HM1-M52H6
- Additional Names:
- HMG1|HMG3|HMGB1|SBP-1
- Physical State:
- Powder
- Molecular Weight:
- 26.8 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- HMGB1
- Species:
- Mouse
- Uniprot:
- P63158-1
- Synonyms:
- High mobility group protein 1
- Extra Details:
- High-mobility group protein B1 (HMGB1) is also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. HMGB1 is a non-histone architectural chromosomal protein ubiquitously present in all vertebrate nuclei and binds double-stranded DNA without sequence specificity. The mechanism of inflammation and damage is binding to TLR4, which mediates HMGB1-dependent activation of macrophage cytokine release. This positions HMGB1 at the intersection of sterile and infectious inflammatory responses. HMGB1 has been studied as a DNA vaccine adjuvant and a target for cancer therapy.
- Shipping Conditions:
- Ambient