HLT-H82E5
Biotinylated Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Complex Protein (Monomer, MALS verified)
Cannot supply to this region.
- SKU:
- HLT-H82E5
- Physical State:
- Powder
- Molecular Weight:
- 36.3 kDa and 11.7 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- HLA-A*0201 & B2M & hTERT (ILAKFLHWL)
- Species:
- Human
- Uniprot:
- P61769
- Synonyms:
- beta chain of MHC class I molecules;beta-2-microglobin;beta-2-microglobulin;IMD43
- Extra Details:
- hTERT (human Telomerase Reverse Transcriptase), the catalytic subunit of telomerase, maintains telomere length to drive tumor cells' unlimited proliferation. It is highly expressed in ~85-90% of cancers but silenced in most normal somatic cells. The peptide ILAKFLHWL (from hTERT residues 540-548) acts as a tumor-specific antigen. It binds to MHC class I molecule HLA-A0201 to form a surface complex on tumors, activating cytotoxic T lymphocytes (CTLs). The Human HLA-A*0201 hTERT (ILAKFLHWL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and ILAKFLHWL peptide of the hTERT.
- Shipping Conditions:
- Ambient