HLT-H82E3
Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Monomer, MALS verified)
Cannot supply to this region.
- SKU:
- HLT-H82E3
- Physical State:
- Powder
- Molecular Weight:
- 36.1 kDa and 11.7 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- HLA-A*0301 & B2M & Survivin Mut (RISTFKNWPK)
- Species:
- Human
- Uniprot:
- P04439-1, P61769-1
- Synonyms:
- Human leukocyte antigen A;MHC class I antigen A*3
- Extra Details:
- The peptide RISTFKNWPK, derived from a survivin mutant, is presented by the HLA-A*03:01/B Beta2m complex and serves as a promising neoantigen target. Its presentation enables cytotoxic T lymphocytes (CTLs) to recognize and attack tumor cells overexpressing this mutated survivin variant, which is often associated with cancer cell survival and therapy resistance, offering a potential avenue for specific immunotherapy.
- Shipping Conditions:
- Ambient