HLR-H82E2
Biotinylated Human HLA-A*11:01&B2M&KRASG12R (VVVGARGVGK) Complex Protein (Monomer, MALS verified)
Cannot supply to this region.
- SKU:
- HLR-H82E2
- Physical State:
- Powder
- Molecular Weight:
- 36.0 kDa and 11.7 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- HLA-A*1101 & B2M & KRASG12R (VVVGARGVGK)
- Species:
- Human
- Uniprot:
- P61769, Q5S3G3-1
- Synonyms:
- beta chain of MHC class I molecules;beta-2-microglobin;beta-2-microglobulin;IMD43
- Extra Details:
- The peptide VVVGARGVGK, derived from the KRAS G12R mutation and presented by the HLA-A*11:01/B Beta2-microglobulin (B Beta2m) complex, is a pivotal antigenic target in antitumor immunity. This complex plays a crucial role by activating specific cytotoxic T lymphocytes (CTLs), enabling the immune system to recognize and eliminate tumor cells harboring the KRAS G12R mutation.
- Shipping Conditions:
- Ambient