PE-Labeled Human HLA-A*02:01&B2M&p53 (HMTEVVRHC) Tetramer Protein

Cannot supply to this region.

SKU:: HLP-HP2HE
Physical State:: Powder
Molecular Weight:: 49.3 kda
Storage Conditions:: Please refer to datasheet
Supplier:: ACRO Biosystems
Buffer:: PBS, 1% BSA, pH7.4
Immunogen:: HLA-A*0201 & B2M & p53 (HMTEVVRHC)
Species:: Human
Uniprot:: P61769-1
Extra Details:: TP53 has been recognized as a tumor suppressor. 50% of cancers carry a TP53 mutation while many others affect other pathway components. High-copy numbers of WT p53 peptide-MHC class I complexes were detected on tumor cells as compared to low copies on normal cells. The Human HLA-A*0201 p53 (HMTEVVRHC) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and HMTEVVRHC peptide of the p53.