Biotinylated Chimeric HLA-A*02:01 (H-2Kb A Alpha3)&B2M&GP100 (YLEPGPVTA) Complex Protein (Monomer, MALS verified)

Cannot supply to this region.

SKU:: HLG-H82E9
Physical State:: Powder
Molecular Weight:: 50.3 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Chimeric HLA-A*0201 (H-2Kb α3) & B2M & GP100(YLEPGPVTA)
Species:: Human, Mouse
Uniprot:: P01901, P61769
Synonyms:: beta chain of MHC class I molecules;beta-2-microglobin;beta-2-microglobulin;class I major histocompatibility antigen H-2Kd;H-2 class I histocompatibility antigen, K-B alpha chain;H-2 class I histocompatibility antigen, K-D alpha chain;H-2 class I histocompatibility antigen, K-K alpha chain;H-2 class I histocompatibility antigen, K-Q alpha chain;H-2 class I histocompatibility antigen, K-W28 alpha chain;H-2K;H-2K(B);H-2K(d);H-2K(K);H-2K(Q);H2-D1;H2-K;H2-K_p;histocompatibility 2, K region, promoter 1;IMD43;K-f;MHC class I antigen;MHC class I H2-K-b-alpha-2 cell surface glycoprotein;MHC class I heavy chain H2-K;MHC class I heavy chain heavy chain;MHC class I heavy chain maturation peptide;MHC class II antigen D;MHC class II antigen K;MHC H2-K transplantation antigen
Extra Details:: Glycoprotein 100, is also well known as gp100 and Melanocyte protein PMEL. This antigen is a melanocyte-specific type I transmembrane glycoprotein and composed of 661 amino acids. Glycoprotein 100 is related to the tumor regression in metastatic melanoma patients after adoptive therapy, by which its epitopes being recognized by tumor lymphocytes and T-cells. The gp100280-288(YLEPGPVTA) was originally shown to be recognized by HLA-A*0201 tumor-infiltrating lymphocytes from melanoma patients, and therefore it is widely been studied in TCR -T studies. The Human HLA-A*0201 Mouse H-2Kb gp100 (YLEPGPVTA) complex protein is a complex of HLA-A*0201 & H-2Kb of the MHC Class I, hB2M and YLEPGPVTA peptide of the gp100.

Shipping Conditions:: Ambient