Biotinylated Human HLA-A*02:01&B2M&gp100 (YLEPGPVTA) Complex Protein (Monomer, MALS verified)

Cannot supply to this region.

SKU:: HLG-H82E6
Additional Names:: HLA-A*02:01 & B2M & GP100
Physical State:: Powder
Molecular Weight:: 36.0 kDa and 13.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: HLA-A*02:01 & B2M & gp100 (YLEPGPVTA)
Species:: Human
Uniprot:: P61769
Synonyms:: beta chain of MHC class I molecules;beta-2-microglobin;beta-2-microglobulin;IMD43
Extra Details:: Glycoprotein 100, is also well known as gp100 and Melanocyte protein PMEL. This antigen is a melanocyte-specific type I transmembrane glycoprotein and composed of 661 amino acids. Glycoprotein 100 is related to the tumor regression in metastatic melanoma patients after adoptive therapy, by which its epitopes being recognized by tumor lymphocytes and T-cells. The gp100280-288(YLEPGPVTA) was originally shown to be recognized by HLA-A*0201 tumor-infiltrating lymphocytes from melanoma patients, and therefore it is widely been studied in TCR -T studies. The Human HLA-A*0201 gp100 (YLEPGPVTA) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and YLEPGPVTA peptide of the gp100.