Biotinylated Human HLA-A*02:01&B2M&insB (HLVEALYLV) Complex Protein (Monomer, MALS verified)

Cannot supply to this region.

SKU:: HLB-H82E4
Physical State:: Powder
Molecular Weight:: 36.4 kDa and 13.8 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: HLA-A*0201 & B2M & insB (HLVEALYLV)
Species:: Human
Uniprot:: P61769-1
Extra Details:: Insulin is a heterodimer formed by connecting the A chain (21 amino acids) and B chain (30 amino acids) through two disulfide bonds (A7-B7, A20-B19). Its three-dimensional structure presents a compact spherical conformation. HLVEALYLV is located at amino acids 10-18 of the B chain, and stabilizes the binding interface between insulin and IR through hydrophobic interactions. By regulating the conformation of insulin, it affects its interaction with downstream signaling molecules. The Human HLA-A*0201 & B2M & insB (HLVEALYLV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and HLVEALYLV peptide of the insB.