APC-Labeled Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer Protein

Cannot supply to this region.

SKU:: HL4-HA2E3
Physical State:: Powder
Molecular Weight:: 36.3 kDa and 11.7 kDa
Storage Conditions:: Please refer to datasheet
Supplier:: ACRO Biosystems
Buffer:: PBS, 1% BSA, 50-150 mM NaCl
Immunogen:: HLA-A*0201 & B2M & MAGE-A4 (GVYDGREHTV)
Species:: Human
Uniprot:: P61769-1
Extra Details:: MHC Class I molecules are expressed on nearly all nucleated cells and present peptides to cytotoxic T-cells (CD8+) to survey for infected or cancerous cells. MAGE-A4 is normally silent in adult tissues (except testes and placenta) but is aberrantly expressed in various tumors (e.g., melanoma, lung cancer), making it a prime target for cancer immunotherapy, including T-cell therapies and vaccines.