Biotinylated Human HLA-A*02:01&B2M&SSX-2 (KASEKIFYV) Complex Protein (Monomer, MALS verified)

Cannot supply to this region.

SKU:: HL2-H82ES
Physical State:: Powder
Molecular Weight:: 36.3 kDa and 11.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: HLA-A*0201 & B2M & SSX-2 (KASEKIFYV)
Species:: Human
Uniprot:: P61769-1
Extra Details:: The peptide KASEKIFYV, derived from the cancer-testis antigen SSX-2, is presented by the HLA-A*02:01/B Beta2-microglobulin (B Beta2m) complex. This peptide-MHC complex is recognized as a tumor-associated antigen and can elicit specific cytotoxic T lymphocyte (CTL) responses. Its presentation on certain tumor cells makes it a potential target for cancer immunotherapy, particularly in cancers where SSX-2 is aberrantly expressed, such as melanoma, synovial sarcoma, and some carcinomas.