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HL1-H82E3

Biotinylated Human HLA-A*24:02&B2M&NY-ESO-1 (LLMWITQCF) Complex Protein (Monomer, MALS verified)

Cannot supply to this region.

SKU:
HL1-H82E3
Physical State:
Liquid
Molecular Weight:
35.8 kDa and 11.7 kDa
Storage Conditions:
-70[o]C
Supplier:
ACRO Biosystems
Buffer:
PBS
Immunogen:
HLA-A*2402 & B2M & NY-ESO-1 (LLMWITQCF)
Species:
Human
Uniprot:
P61769
Synonyms:
beta chain of MHC class I molecules;beta-2-microglobin;beta-2-microglobulin;IMD43
Extra Details:
NY-ESO-1, which is also well-known as New York esophageal squamous cell carcinoma 1, is an efficient target for cancer immunotherapy. This antigen is a member of cancer-testis antigens (CTAs) and is highly expressed in various cancers, including melanoma, ovarian, cervical cancer, etc. Adoptive T cell therapy with HLA-A24 restricted NY-ESO-1 transduced CD8+ T cells has improved the clinical response rates and overall survival of treatment-refractory melanoma patients. The Human HLA-A*2402 NY-ESO-1 (LLMWITQCF) complex protein is a complex of HLA-A*2402 of the MHC Class I, B2M and LLMWITQCF peptide of the NY-ESO-1.
Shipping Conditions:
Dry Ice