HC2-H5224
Human Serpin D1 / Heparin Cofactor II Protein, His Tag
Cannot supply to this region.
- SKU:
- HC2-H5224
- Additional Names:
- HC-II|HCF2|HLS2|SerpinD1
- Physical State:
- Powder
- Molecular Weight:
- 55.7 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 150 mM NaCl, pH7.5
- Immunogen:
- Serpin D1
- Species:
- Human
- Extra Details:
- Serpin D1 is also known as Heparin cofactor 2 (HCF2), Protease inhibitor leuserpin-2 (HLS2), Heparin cofactor II (HC-II), which belongs to the serpin family. HCF2 is expressed predominantly in liver. Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, SerpinD1 / HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). In a glycosaminoglycan-independent manner, serpinD1 / HC-II also inhibits chymotrypsin. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
- Shipping Conditions:
- Ambient