GTF-H5253
Human CTGF / CCN2 Protein, Fc Tag
Cannot supply to this region.
- SKU:
- GTF-H5253
- Additional Names:
- CCN2|HCS24|IBP-8|IGF-binding protein 8|IGFBP-8|IGFBP8|NOV2
- Physical State:
- Powder
- Molecular Weight:
- 61.9 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Immunogen:
- CTGF
- Species:
- Human
- Uniprot:
- Q5M8T4-1
- Extra Details:
- Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.
- Shipping Conditions:
- Ambient