GRA-H5255
Human GM-CSF R alpha Protein, Fc Tag
Cannot supply to this region.
- SKU:
- GRA-H5255
- Additional Names:
- CD116|CDw116|CSF2R|CSF2RA|CSF2RY|GM-CSF R alpha|GM-CSF-R-alpha|GMCSFR-alpha|GMR-alpha
- Physical State:
- Powder
- Molecular Weight:
- 60.9 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- Tris with Glycine, Arginine and NaCl, pH7.5
- Immunogen:
- GM-CSF R alpha
- Species:
- Human
- Uniprot:
- P15509-1
- Synonyms:
- CDw116
- Extra Details:
- GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor A Alpha-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.
- Shipping Conditions:
- Ambient