GPR-H52H3
Human gp130 & OSMR Heterodimer Protein, His Tag (MALS verified)
Cannot supply to this region.
- SKU:
- GPR-H52H3
- Physical State:
- Powder
- Molecular Weight:
- 151.8 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- gp130 & OSMR
- Species:
- Human
- Uniprot:
- P40189-1, Q99650-1
- Synonyms:
- CDw130;Interleukin-31 receptor subunit beta;Interleukin-6 signal transducer;Membrane glycoprotein 130;Oncostatin-M receptor subunit alpha
- Extra Details:
- OSM signaling on responsive cells is mediated by binding to two distinct signaling receptor complexes identified as type I and type II OSM receptors. Type II OSM receptor (gp130/OSMRB Beta) is a heterodimer composed of gp130 and OSM receptor B Beta subunit. The type II receptor has OSM specificity. This receptor triggers the activation of associated Janus kinases (JAKs), leading primarily to the phosphorylation and activation of the Signal Transducer and Activator of Transcription 3 (STAT3) pathway.
- Shipping Conditions:
- Ambient