Human GPRC5D Full Length Protein, Flag,His Tag (Detergent)

Cannot supply to this region.

SKU:: GPD-H52D5
Physical State:: Liquid
Molecular Weight:: 37.9 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Immunogen:: GPRC5D
Species:: Human
Uniprot:: Q9NZD1-2
Extra Details:: GPRC5D is an orphan G protein-coupled receptor (GPCR) with highly restricted expression in hair follicles, yet it is specifically and uniformly overexpressed on malignant plasma cells in multiple myeloma (MM). This unique expression profile makes it an ideal immunotherapy target, leading to the development of approved bispecific antibodies like talquetamab and promising CAR-T therapies for MM