Human GPR75 Full Length Protein (VLP)

Cannot supply to this region.

SKU:: GP5-H52P3
Physical State:: Liquid
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS, Arginine, pH7.4
Immunogen:: GPR75
Species:: Human
Uniprot:: O95800
Synonyms:: GPRchr2;probable G-protein coupled receptor 75;WI31133
Extra Details:: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.