GP5-H52D3
Human GPR75 Full Length Protein, Flag,His Tag (Detergent)
Cannot supply to this region.
- SKU:
- GP5-H52D3
- Physical State:
- Liquid
- Molecular Weight:
- 78.4 kDa
- Storage Conditions:
- -70[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
- Immunogen:
- GPR75
- Species:
- Human
- Uniprot:
- O95800
- Synonyms:
- GPRchr2;probable G-protein coupled receptor 75;WI31133
- Extra Details:
- G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
- Shipping Conditions:
- Dry Ice