GMP-L18H16
GMP Human IL-18 Protein
Cannot supply to this region.
- SKU:
- GMP-L18H16
- Physical State:
- Powder
- Molecular Weight:
- 18.2 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- ABP:
- No Import Docs
- Buffer:
- PBS
- Immunogen:
- IL-18
- Species:
- Human
- Uniprot:
- Q14116
- Synonyms:
- iboctadekin;IFN-gamma-inducing factor;IGIF;IL-1 gamma;IL-18;IL-1g;IL1F4;Interferon gamma-inducing factor;interleukin 18 (interferon-gamma-inducing factor);interleukin-1 gamma;interleukin-18
- Extra Details:
- Interleukin-18 (IL-18) is a potent proinflammatory cytokine that induces interferon-G Gamma (IFN-G Gamma) production from T helper type 1 (Th1) cells and natural killer (NK) cells, particularly in the presence of IL-12. IL-18 also participates in the developmental regulation of Th1 cells and mediates Fas-mediated cytotoxicity. Suppression of IL-18 activity is being investigated for the treatment of chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis. IL-18 exerts its biological functions by inducing heterodimerization of the two subunits of its receptor, IL-18RA Alpha and IL-18RB Beta. These subunits share structural homology with members of the IL-1 receptor superfamily.
- Shipping Conditions:
- Blue Ice