Rabbit Growth Hormone R (GHR) Protein, His Tag

Cannot supply to this region.

SKU:: GHR-R52H9
Additional Names:: GH receptor|GHBP|GHR
Physical State:: Powder
Molecular Weight:: 29.3 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Growth Hormone R
Species:: Rabbit
Uniprot:: P19941-1
Synonyms:: Somatotropin receptor
Extra Details:: Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormone-binding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin type-III domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.