GFA-M52H7
Mouse GFR alpha-like Protein, His Tag
Cannot supply to this region.
- SKU:
- GFA-M52H7
- Additional Names:
- GFR alpha like|GFR alpha-like|GFRAL|GRAL
- Physical State:
- Powder
- Molecular Weight:
- 39.0 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- ABP:
- No Import Docs
- Buffer:
- PBS
- Immunogen:
- GFR alpha-like
- Species:
- Mouse
- Uniprot:
- Q6SJE0-1
- Extra Details:
- GFR alpha-like is also known as GDNF family receptor alpha-like, GFRAL, C6orf144, UNQ9356, PRO34128. Growth differentiation factor-15 (GDF15) is a circulating protein that has been implicated in multiple biological processes, including energy homeostasis, body weight regulation, and cachexia driven by cancer and chronic disease. GDNF family receptor A Alpha-like (GFRAL) was recently identified as the neuronal brainstem receptor responsible for mediating the anorectic actions of GDF15. Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses . Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
- Shipping Conditions:
- Ambient