GD8-H5343
Human latent GDF-8 Protein, His Tag, low endotoxin (MALS verified)
Cannot supply to this region.
- SKU:
- GD8-H5343
- Physical State:
- Powder
- Molecular Weight:
- 42.0 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- GDF-8
- Species:
- Human
- Uniprot:
- O14793-1
- Synonyms:
- Myostatin
- Extra Details:
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
- Shipping Conditions:
- Ambient