Human GCGR / Glucagon receptor Protein, Fc Tag, low Endotoxin (MALS verified)

Cannot supply to this region.

SKU:: GCR-H53H3
Physical State:: Powder
Molecular Weight:: 39.5 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: GCGR
Species:: Human
Uniprot:: P47871-1
Extra Details:: The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of type 2 diabetes mellitus (T2DM) . The ever increasing prevalence of type 2 diabetes mellitus in the developed and developing nations calls for the introduction of new and more effective treatments. Glucagon receptor (GCGR) antagonists are highly validated in preclinical models of T2DM and thus have the potential to be developed as a new therapy.