Human GCGR / Glucagon receptor Protein, His Tag, low endotoxin (MALS verified)

Cannot supply to this region.

SKU:: GCR-H52H3
Additional Names:: GCGR|Glucagon R|Glucagon receptor
Physical State:: Powder
Molecular Weight:: 14.9 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: GCGR
Species:: Human
Uniprot:: P47871-1
Extra Details:: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.