HRP conjugated Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016)

Cannot supply to this region.

SKU:: G4S-HLY25G1
Physical State:: Powder
Storage Conditions:: Please refer to datasheet
Supplier:: ACRO Biosystems
Reactivities:: Rabbit
Buffer:: PBS (pH 7.4) containing 0.01% PF68
Immunogen:: G4S linker
Clone:: 016
Extra Details:: The G4S linker is emerged as the most common linking peptides for scFvs. It is composed of the repeated sequence (Gly-Gly-Gly-Gly-Ser) and commonly found as either a 15-mer (G4S)3 or 20-mer(G4S)4 within scFv fragments. The G4S linker has become an integral part of the vast majority of CARs as it links the VH and VL recognition domains of scFvs. The G4S linker is commonly used in CARs targeting solid tumor antigens, such as HER2 and CEA, while the whitlow/218 linker peptide is predominantly used in CAR constructs targeting hematological malignancies such as CD19 CAR products.