FZ5-H5259
Human Frizzled-5 / FZD5 Protein, Fc Tag (MALS verified)
Cannot supply to this region.
- SKU:
- FZ5-H5259
- Additional Names:
- C2orf31|Frizzled-5|Fz-5|FZD5|FzE5|hFz5
- Physical State:
- Powder
- Molecular Weight:
- 42.6 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- Frizzled-5
- Species:
- Human
- Uniprot:
- Q13467
- Synonyms:
- C2orf31;frizzled 5, seven transmembrane spanning receptor;frizzled family receptor 5;frizzled-5;fz-5;fzE5;HFZ5;seven-transmembrane receptor frizzled-5;Wnt receptor
- Extra Details:
- Frizzled-5 (FZD5) is also known as FzE5, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the beta-catenin pathway. FZD5 interacts with GOPC.
- Shipping Conditions:
- Ambient