FG0-H5115
Human FGF-10 / KGF 2 Protein, premium grade
Cannot supply to this region.
- SKU:
- FG0-H5115
- Physical State:
- Powder
- Molecular Weight:
- 19.3 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 20 mM MOPS, 50 mM Na2SO4, 0.5 mM EDTA, pH7.2
- Immunogen:
- FGF-10
- Species:
- Human
- Uniprot:
- O15520-1
- Synonyms:
- Keratinocyte growth factor 2
- Extra Details:
- Fibroblast Growth Factor 10 (FGF 10) is an evolutionary conserved secreted growth factor mediating mostly mesenchymal to epithelial signaling. FGF 10 belongs to the FGF 7 subfamily and shares similar biochemical and amino acid sequences with its constituent members (FGF3, FGF 7 and FGF 22). As a paracrine FGF, FGF 10 elicits its biological responses by activating the fibroblast growth factor receptor 2b (FGF R 2b), is crucial for governing proximal distal outgrowth as well as patterning and acts upstream of the known apical ectodermal ridge (AER) marker FGF 8. FGF10 is also implicated in pancreatic cancer, and that overexpression of FGFR2b is associated with metastatic invasion.
- Shipping Conditions:
- Ambient