Biotinylated Mouse FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: FCM-M82W5
Additional Names:: FCGRT & B2M|FcRn
Physical State:: Powder
Molecular Weight:: 34.9 kDa (FCGRT) & 11.6 kDa (B2M)
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: FcRn (FCGRT & B2M)
Species:: Mouse
Uniprot:: P01887-1, Q61559-1
Synonyms:: IgG Fc fragment receptor transporter alpha chain;Neonatal Fc receptor
Extra Details:: FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.