FC4-M52H3
Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified)
Cannot supply to this region.
- SKU:
- FC4-M52H3
- Additional Names:
- CD16-2|Fc gamma RIV|Fcgr4
- Physical State:
- Powder
- Molecular Weight:
- 22.8 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- Fc gamma RIV / CD16-2
- Species:
- Mouse
- Uniprot:
- A0A0B4J1G0-1
- Synonyms:
- CD16-2;FcgammaRIV
- Extra Details:
- FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions
- Shipping Conditions:
- Ambient