Biotinylated Human EphA2 Protein, His,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: EP2-H82E4
Physical State:: Powder
Molecular Weight:: 59.8 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: EphA2
Species:: Human
Uniprot:: P29317
Synonyms:: ARCC2;CTPA;CTPP1;CTRCT6;ECK;ephrin type-A receptor 2;Epithelial cell kinase;epithelial cell receptor protein tyrosine kinase;soluble EPHA2 variant 1;tyrosine-protein kinase receptor ECK
Extra Details:: EphA2 is a member of the Eph receptor tyrosine kinase family, widely involved in cell adhesion, migration, and tissue boundary formation. It is frequently overexpressed in multiple solid tumors, including breast, lung, ovarian, and pancreatic cancers, where it drives tumor progression, angiogenesis, and metastasis. EphA2 signaling is activated by ephrin-A ligands and contributes to oncogenic pathways such as MAPK and PI3K. Because of its high tumor selectivity and surface accessibility, EphA2 is a prominent therapeutic target for antibodies, ADCs, and CAR-T therapies.