Human Endoglin / CD105 Protein, His Tag

Cannot supply to this region.

SKU:: ENN-H52H9
Additional Names:: CD105|END|Endoglin|ENG
Physical State:: Powder
Molecular Weight:: 62.6 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: PBS
Immunogen:: Endoglin
Species:: Human
Uniprot:: P17813-1
Extra Details:: Endoglin (ENG), endothelial glycoprotein, also known as CD105, is a coreceptor of the transforming growth factor-B Beta (TGFB Beta) family signaling complex, which is highly expressed on endothelial cells and plays a key role in angiogenesis. It regulates the responses associated with binding to transforming growth factor B Beta1 egg (Activin-A), bone morphogenetic protein 2 (BMP-2), and bone morphogenetic protein 7 (BMP-7). Endoglin may be involved in autosomal dominant disease, such as hereditary hemorrhagic telangiectasia 1 (HHT1). Circulating soluble ENG is also elevated in pulmonary arterial hypertension(PAH) and is proposed to be a biomarker for the prognosis of group I PAH patients.