Human ENPP-2 / Autotaxin Protein, His Tag (active enzyme)

Cannot supply to this region.

SKU:: EN2-H5241
Additional Names:: ATX|ATX-X|Autotaxin|E-NPP 2|ENPP-2|LysoPLD|NPP2|PD-IALPHA|PDNP2
Physical State:: Powder
Molecular Weight:: 94.5 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 150 mM NaCl, pH7.5
Immunogen:: ENPP-2
Species:: Human
Extra Details:: Autotaxin also known as ectonucleotide pyrophosphatase / phosphodiesterase family member 2 (E-NPP 2 or ENPP2), Extracellular lysophospholipase D (LysoPLD), Autotaxin (ATX or ATX-X), which belongs to the nucleotide pyrophosphatase / phosphodiesterase family. ENPP2 contains two SMB (somatomedin-B) domains. ENPP2 hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. ENPP2 can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. ENPP2 stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein.