Human ENPP1 Protein, His Tag (active enzyme)

Cannot supply to this region.

SKU:: EN1-H5243
Physical State:: Powder
Molecular Weight:: 97.0 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 150 mM NaCl, pH7.5
Immunogen:: ENPP1
Species:: Human
Uniprot:: P22413
Synonyms:: alkaline phosphodiesterase 1;ARHR2;COLED;E-NPP 1;ectonucleotide pyrophosphatase/phosphodiesterase family member 1;Ly-41 antigen;M6S1;Membrane component chromosome 6 surface marker 1;membrane component, chromosome 6, surface marker 1;NPP1;NPPS;PC-1;PCA1;PDNP1;phosphodiesterase I/nucleotide pyrophosphatase 1;plasma-cell membrane glycoprotein 1;plasma-cell membrane glycoprotein PC-1
Extra Details:: ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) is a membrane-bound glycoprotein that regulates extracellular nucleotide metabolism. It hydrolyzes ATP to AMP and pyrophosphate, thereby controlling mineralization processes and signaling pathways. ENPP1 plays a critical role in bone and cartilage development, insulin signaling, and vascular calcification. Mutations in ENPP1 are linked to rare genetic disorders such as generalized arterial calcification of infancy and autosomal recessive hypophosphatemic rickets. Because of its dual involvement in skeletal biology and metabolic regulation, ENPP1 has become an important target for both diagnostic research and therapeutic development.