ADC Isotype Control Mouse IgG2a (Exatecan)

Cannot supply to this region.

SKU:: DNP-DM487
Physical State:: Powder
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Reactivities:: Mouse
Buffer:: PBS (pH 7.4)
Immunogen:: IgG Control
Clone:: Exatecan
Extra Details:: Exatecan is a semi-synthetic camptothecin-derived topoisomerase I inhibitor. It specifically binds to and inhibits topoisomerase I, blocking DNA replication and transcription processes to potently suppress tumor cell proliferation. As a highly active cytotoxic payload, it serves as a core component of multiple antibody-drug conjugates (ADCs) and is widely used in the research, development and clinical translation of targeted anti-tumor ADC drugs.