ADC Isotype Control Mouse IgG2a (MMAF)

Cannot supply to this region.

SKU:: DNP-CM487
Physical State:: Powder
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Reactivities:: Mouse
Buffer:: PBS (pH 7.4)
Immunogen:: IgG Control
Clone:: MMAF
Extra Details:: MMAF (Monomethyl auristatin F) is an auristatin-derived microtubule inhibitor. With a mechanism of action similar to MMAE, it inhibits tumor cell proliferation by interfering with microtubule dynamics, yet exhibits superior water solubility and plasma stability with lower off-target toxicity. As a cytotoxic payload for ADCs, it is suitable for developing anti-tumor ADCs for MMAE-resistant cases or those requiring reduced systemic toxicity.