Human DDC / Dopa Decarboxilase Protein, His Tag (MALS verified)

Cannot supply to this region.

SKU:: DDC-H55H6
Physical State:: Liquid
Molecular Weight:: 55.8 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 25 mM MES, 150 mM NaCl, pH6.0
Immunogen:: DDC
Species:: Human
Uniprot:: P20711-1
Synonyms:: DOPA decarboxylase
Extra Details:: Dopa decarboxilase (DDC), also known as aromatic amino acid decarboxylase, is a group II decarboxylase. The enzyme catalyzes the decarboxylation of aromatic L-amino acids to produce the corresponding amines. DDC produces the neurotransmitters dopamine and serotonin from L-Dopa and L-5-hydroxytryptophan, respectively. DDC inhibitors is in clinical use to treat Parkinson's disease(PD), usually co-administrated with L-DOPA. DDC would block peripheral conversion to dopamine and allow a greater percentage of L-DOPA to reach the brain, causing an increase in brain dopamine levels, and reducing the side effects of dopamine-rich blood.