Human DcR3 / TNFRSF6B Protein, His Tag, low endotoxin (MALS verified)

Cannot supply to this region.

SKU:: DC3-H52H3
Physical State:: Powder
Molecular Weight:: 20.1 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: DcR3
Species:: Human
Uniprot:: O95407
Synonyms:: DCR3;Decoy receptor 3;decoy receptor 3 variant 1;decoy receptor 3 variant 2;decoy receptor for Fas ligand;DJ583P15.1.1;M68;M68E;TR6;tumor necrosis factor receptor superfamily member 6B;tumor necrosis factor receptor superfamily, member 6b, decoy
Extra Details:: Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.