Human CXCR2 Protein, Flag,His Tag (Detergent)

Cannot supply to this region.

SKU:: CX2-H55D3
Physical State:: Liquid
Molecular Weight:: 43.0 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM HEPES, 150 mM NaCl, DDM, pH7.5, CHS
Immunogen:: CXCR2
Species:: Human
Uniprot:: P25025
Synonyms:: C-X-C chemokine receptor type 2;CD182;CDw128b;chemokine (CXC) receptor 2;CMKAR2;CXC-R2;CXCR-2;CXCR2 gene for IL8 receptor type B;GRO/MGSA receptor;high affinity interleukin-8 receptor B;IL-8 receptor type 2;IL-8R B;IL8R2;IL8RA;IL8RB;interleukin 8 receptor type 2;interleukin 8 receptor, beta;interleukin-8 receptor type B;WHIMS2
Extra Details:: CXCR2 is a chemokine receptor mediating neutrophil recruitment and angiogenesis via ELR+ CXC chemokines (IL-8). It is a central driver of tumor-promoting inflammation and myeloid-derived suppressor cell (MDSC) accumulation. CXCR2 antagonists aim to remodel the tumor immune microenvironment and enhance checkpoint inhibitor efficacy.