Biotinylated Human CX3CL1 Protein, His Tag, ultra sensitivity (primary amine labeling)

Cannot supply to this region.

SKU:: CX1-H8221
Additional Names:: CX3CL1|Fractalkine
Physical State:: Powder
Molecular Weight:: 35.5 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: CX3CL1
Species:: Human
Extra Details:: Fractalkine is also known as C-X3-C motif chemokine 1 (CX3CL1) and neurotactin. Fractalkine is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells. It has also been found to be essential for microglial cell migration. CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.