Mouse COL1A1 Protein, His Tag, low endotoxin (MALS verified)

Cannot supply to this region.

SKU:: CO1-M5243
Physical State:: Powder
Molecular Weight:: 28.8 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 150 mM NaCl, pH7.5
Immunogen:: COL1A1
Species:: Mouse
Uniprot:: P11087
Synonyms:: alpha-1 type 1 collagen;alpha-1 type I collagen;Co;Col;Col1;Col1a-1;Cola-1;Cola1;collagen alpha-1(I) chain;Mov-;Mov-13;Mov13;procollagen, type I, alpha 1
Extra Details:: Type I collagen is the most abundant structural protein of connective tissues such as skin, bone and tendon. It is synthesized as a procollagen molecule which is characterized by a 300 nm triple helical domain flanked by globular N- and C-terminal propeptides. The triple helical domain contains Gly-Xaa-Yaa triplets where Xaa and Yaa are frequently proline and hydroxyproline, respectively. The non-helical propeptides are removed by procollagen N- and C-proteinase activities so that the mature triple helices can self-assemble into collagen fibrils that provide tensile strength to tissues. Type I collagen is a heterotrimer that consists of two alpha 1(I) chains and one alpha 2(I) chain, although homotrimers consisting of three identical alpha 1(I) chains have also been described .