Biotinylated Human CNTF R alpha Protein, His,Avitag[TM]

Cannot supply to this region.

SKU:: CNR-H82Q3
Physical State:: Powder
Molecular Weight:: 39.8 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: CNTF R alpha
Species:: Human
Uniprot:: P26992
Synonyms:: ciliary neurotrophic factor receptor subunit alpha;CNTF receptor subunit alpha;CNTFR-alpha
Extra Details:: CNTF receptor alpha (CNTFR) is a specialized protein primarily expressed in the nervous system and skeletal muscle. Unlike many receptors, it lacks a transmembrane domain and anchors to the cell surface via a GPI linkage. It functions as a crucial signaling component that binds Ciliary Neurotrophic Factor, subsequently recruiting gp130 and LIFR to initiate the JAK/STAT pathway. This process is vital for promoting neuronal survival, guiding motor neuron development, and regulating muscle regeneration.