Human CLEC4C / BDCA2 Protein, His Tag

Cannot supply to this region.

SKU:: CLC-H5245
Additional Names:: BDCA-2|CD303|CLEC4C|CLECSF11|CLECSF7|DLEC|HECL
Physical State:: Powder
Molecular Weight:: 26.6 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: PBS
Immunogen:: CLEC4C
Species:: Human
Uniprot:: Q8WTT0-1
Synonyms:: Blood dendritic cell antigen 2;C-type lectin superfamily member 7;Dendritic lectin
Extra Details:: CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.