Rat Clec4b2 Protein, His Tag

Cannot supply to this region.

SKU:: CLB-R5246
Physical State:: Powder
Molecular Weight:: 21.6 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
ABP:: No Import Docs
Buffer:: PBS
Immunogen:: Clec4b2
Species:: Rat
Uniprot:: F1M7G4-1
Extra Details:: CLEC4B2 (C-type Lectin domain family 4, member b2), also called dendritic cell immunoactivating receptor 1 (DCAR1) and antigen presenting cell lectin-like receptor A1 (APLRA1), is a type II membrane protein belonging to the cell surface C-type lectin domain family. CLEC4B2 potentially has a second role in host defense. Clec4b2 is a functional receptor on cells of the immune system and provides further insights into the regulation of immune responses by CLRs. CLEC4B2 is specifically required for the innate immune response to fungal infection and wounding and place this GPCR further upstream than any other known component of innate immune recognition and signaling in C. elegans epidermis.