Rat CLEC12A / MICL / CLL-1 Protein, His Tag

Cannot supply to this region.

SKU:: CLA-R5248
Additional Names:: CD371|CLEC12A|CLL-1|CLL1|DCAL-2|DCAL2|MICL
Physical State:: Powder
Molecular Weight:: 26.0 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: CLEC12A
Species:: Rat
Uniprot:: B4F798-1
Extra Details:: CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.