Human Claudin-1 Full Length Protein, His Tag (Nanodisc-pro)

Cannot supply to this region.

SKU:: CL1-H55H3
Physical State:: Liquid
Molecular Weight:: 84.6 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 20 mM HEPES, 150 mM NaCl, pH7.3
Immunogen:: Claudin-1
Species:: Human
Uniprot:: O95832
Synonyms:: claudin-1;CLD1;ILVASC;SEMP1;Senescence-associated epithelial membrane protein;senescence-associated epithelial membrane protein 1
Extra Details:: A widely expressed tight junction protein essential for epidermal barrier function and liver homeostasis. It is a critical host co-receptor for Hepatitis C Virus (HCV) entry, making it a historical antiviral target. In cancer, Claudin-1 overexpression promotes invasion and is linked to colorectal and liver tumor progression.