Human Claudin-1 Full Length Protein (VLP)

Cannot supply to this region.

SKU:: CL1-H52P6
Physical State:: Liquid
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS, Arginine, pH7.4
Immunogen:: Claudin-1
Species:: Human
Uniprot:: O95832
Synonyms:: claudin-1;CLD1;ILVASC;SEMP1;Senescence-associated epithelial membrane protein;senescence-associated epithelial membrane protein 1
Extra Details:: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]