HEK293/Human TrkA Stable Cell Line

Cannot supply to this region.

SKU:: CHEK-ATP192
Application:: ELISA, Flow Cytometry, FuncS
Physical State:: Liquid
Storage Conditions:: Liquid N2
Supplier:: ACRO Biosystems
Immunogen:: TrkA
Species:: Human
Extra Details:: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]