CDL-H5255
Human CD27 Ligand / CD70 Protein, Llama IgG2b Fc Tag, low endotoxin
Cannot supply to this region.
- SKU:
- CDL-H5255
- Additional Names:
- CD27L|CD27LG|CD70|TNFSF7|TNFSF7G
- Physical State:
- Powder
- Molecular Weight:
- 75.5 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Immunogen:
- CD27 Ligand
- Species:
- Human
- Extra Details:
- Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNG Gamma production, on NK cells.
- Shipping Conditions:
- Ambient