CDH-H5251
Human CD28H / IGPR-1 Protein, Fc Tag (MALS verified)
Cannot supply to this region.
- SKU:
- CDH-H5251
- Additional Names:
- IGPR1|TMIGD2
- Physical State:
- Powder
- Molecular Weight:
- 40.6 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- CD28H
- Species:
- Human
- Uniprot:
- Q96BF3-1
- Synonyms:
- CD28 homolog;Immunoglobulin and proline-rich receptor 1
- Extra Details:
- CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
- Shipping Conditions:
- Ambient