Human CD79A&CD79B Heterodimer Protein, Mouse IgG2a Fc,Flag Tag&Mouse IgG2a Fc,His Tag (MALS verified)

Cannot supply to this region.

SKU:: CDB-H52W3
Additional Names:: B-cell antigen receptor complex-associated protein alpha chain|B-cell antigen receptor complex-associated protein beta chain|CD79A&CD79B
Physical State:: Powder
Molecular Weight:: 43.8 kDa & 46.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Immunogen:: CD79A & CD79B
Species:: Human
Uniprot:: P11912-1, P40259-1
Synonyms:: B-cell-specific glycoprotein B29;Ig-alpha;Ig-beta;Immunoglobulin-associated B29 protein;MB-1 membrane glycoprotein;Membrane-bound immunoglobulin-associated protein;Surface IgM-associated protein
Extra Details:: CD79a and CD79b heterodimers are the important signaling components of B cell receptor (BCR) complex which plays a crucial role in B cell development and antibody production. BCR complexes are composed of a ligand-binding receptor (membrane immunoglobulin; mIg), non-covalently associated with the signaling com-ponent, a disulfide-linked heterodimer of CD79a (IgA Alpha) and CD79b (IgB Beta). Both CD79 subunits consist of an Ig-like domain, a transmembrane (TM) region, and a longer cytoplasmic tail (CYT) containing an immune-receptor tyrosine-based activation motif (ITAM).